Silfamin is a bioactive fraction derived from a combination of two Indonesian herbal plants, jinten hitam lokal and mahkota dewa. In Indonesian traditional medicine, jinten hitam lokal and mahkota dewa play significant roles in maintaining health and treating various conditions. Both are used to boost immunity, and support digestive health. Silfamin has shown its effect in stimulating the immune system and treating colds that are accompanied with sore throat.
Product Overview
Botanical origin
Mahkota Dewa pericarpium
Jinten Hitam Lokal seed
Type of extract
Dry extract
Analytical markers: Phalerin and Total Phenolic Compounds
Product Specification
1. Premium Quality and Standardization
Silfamin is a standardized herbal extract crafted to meet stringent quality specifications.
2. Manufactured in a Certified Facility
Produced in a facility with GMP, CPOTB, IEBA and ISO22000 certifications, ensuring top-tier quality.
Guaranteed Halal through the implementation of the Halal Assurance System.
3. Proven Safety Through Rigorous Studies
Acute and subchronic toxicity studies exhibited Silfamin as a non-toxic substance, indicated by the LD50 value greater than 15 g/kg body weight. Furthermore, a 90 days repeated dose of Silfamin revealed no changes in the blood biochemistry profile, animal behavior and activity, or abnormalities in animal organs.
Teratogenicity studies, which evaluate the safety of substances during pregnancy, have shown that Silfamin is non-teratogenic, meaning it does not pose any risk to fetal development.
4. Proven Benefits through Pre-clinical Study
Several preclinical studies have indicated that Silfamin is an effective immunomodulator, demonstrating its capability to stimulate the immune system. Additional research employing the carrageenan-induced paw edema method in mice has further confirmed the anti-inflammatory properties of Silfamin. Treatment with Silfamin resulted in a significant reduction in edema, highlighting its anti-inflammatory effects. Furthermore, studies on mice have shown that Silfamin also produces antipyretic effects.
Key Feature of the Product
Empirical benefit
Mahkota dewa has a rich history of empirical use in Indonesian traditional medicine. It is valued for its perceived health benefits, including pain relief, hormonal balance, detoxification and immune support. Jinten hitam lokal is an essential plant in Indonesian traditional medicine, with a wide range of empirical uses for supporting immune health, respiratory function, digestion, skin health, and hormonal balance.
Health benefits of each herbal composition of Silfamin
Mahkota dewa is highly valued for its anti-inflammatory, immune-boosting, analgesic, and detoxifying properties. In Silfamin, mahkota dewa stimulates the immune system, and exerts an anti-inflammatory and antipyretic effect.
Jinten hitam lokal is also highly valued for its anti-inflammatory, antioxidant, antimicrobial, and anti-cancer properties. In Silfamin, jinten hitam lokal also supports immune health and exerts an anti-inflammatory and antipyretic effect.
Proven effective for stimulating the immune system and treating colds based on pre-clinical studies and literature studies data
Based on previous pre-clinical studies, Silfamin has been shown to promote the elimination rate of carbon particles, increased the phagocytic index, organ mass index, and body weight, enhanced peritoneal macrophage activity, specific immune response, production of IFN gamma, and splenocyte proliferation in mice. These studies concluded that Silfamin can effectively stimulate the immune system. Furthermore, Silfamin demonstrated a reduction in the temperature of test animals induced by peptone, indicating that it also possesses antipyretic effects.
Health Benefit
Store at room temperature (≤ 30°C), in a tight container, protect from direct sunlight.
Storage Conditions
Product information of HerbaCOLD