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Psidii

Psidium guajava

Psidii

Psidii is an herbal product that contains an extract from Psidium guajava leaves. Clinical trials have shown that this product effectively increases platelet count in patients with dengue fever. 


Psidii is available in two dosage forms–capsule and syrup, providing options for individual preferences.

A Brief Introduction to Our Product

A study indicates that guava leaf extract can inhibit the activity of the reverse transcriptase enzyme from the Dengue virus. 


In a preclinical study conducted on mice, it was observed that guava leaf extract increases the number of megakaryocytes in the bone marrow, thereby raising the platelet count in the blood.


Additionally, a study suggests that guava leaf extract may reduce vascular permeability, indicating its potential to prevent plasma leakage and shock, conditions that can lead to death.

Product Functions

Clinical trials were conducted on pediatric and adult patients who experienced grade I and II dengue hemorrhagic fever. The selected criteria for these patients included a sudden high fever of unknown origin lasting continuously for 2 to 7 days, along with bleeding manifestations, liver enlargement, plasma leakage, thrombocytopenia (platelet count below 100,000/μL), and hemoconcentration. The results indicated that guava leaf extract could increase platelet counts from below 100,000/μL to 300,000/μL by the third day of treatment. 


In another clinical study, pediatric patients who consumed guava leaf extract syrup showed an increase in platelet count from 39,750/μL on the third day of fever to 136,000/μL by the fifth day.


Furthermore, other clinical studies indicated that patients who received Psidii capsules showed an increase in platelet count to ≥ 100,000/μL by the fifth day of treatment. The administration of Psidium guajava extract can serve as an alternative therapy to help accelerate the increase in platelet count, potentially reducing the overall duration of treatment.

Insights and Discoveries

Dosage and administration

Capsule

1-2 capsule, 3 times daily

Syrup

2-13 years old: 5 ml, 3 times daily

>13 years old: 10 ml, 3 times daily


Contraindications

Psidii is contraindicated for individuals who are allergic or hypersensitive to any of its components.

Recommendations for Safe Administration and Use of Our Product

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Our Patent Rights

Store at a temperature below 30°C, in a dry place, and protect from direct sunlight. 

Kept out of reach of children.

Storage Conditions

Psidii has been registered and is available in the market in Cambodia and  Philippines (Thrombolief). 

Explore Our Global Markets

  1. Pengaruh Pemberian Ekstrak Psidium guajava terhadap Jumlah Trombosit pada Penderita Demam Berdarah Dengue di Bangsal Rawat Inap Penyakit Dalam RSUD Dr. Saiful Anwar Malang (2001)

  2. Uji Klinik Multisenter Sirup Ekstrak Daun Jambu Biji pada Penderita Demam Berdarah Dengue (2008)

  3. Effect of Psidii Folium Extract in Increasing Thrombocyte Acceleration in Patients with Dengue Fever at Internal Medicine, Dr. Sardjito Hospital, Yogyakarta

  4. Pengaruh Pemberian Sirup Ekstrak Daun Jambu Biji (Psidium Guajava L) Terhadap Jumlah Trombosit Penderita Demam Berdarah Dengue Dewasa Derajat I dan II 

Our Published Research and Articles

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