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Galatonol

Galatonol is a standardized water extract derived from a combination of Sauropus androgynus leaves and Coleus amboinicus herb, with the ratio of 60% and 40%, respectively. Both plants are well-recognized, especially in Indonesia, for their traditional use in increasing breast milk production in lactating mothers.

Product Overview

Botanical origin

Sauropus androgynus folium

Coleus amboinicus herba


Type of extract

Dry extract


Analytical markers: Kaempferol and Total Flavonoids Content

Product Specification

1. Premium Quality and Standardization

Galatonol is a standardized herbal extract crafted to meet stringent quality specifications.


2. Manufactured in a Certified Facility

  • Produced in a facility with Good Manufacturing Practice (GMP), CPOTB, IEBA and ISO 22000 certifications, ensuring top-tier quality.

  • Guaranteed Halal through the implementation of the Halal Assurance System.


3. Proven Safety Through Rigorous Studies

The safety of Galatonol has been evaluated through acute and subchronic oral toxicity studies. The finding revealed an LD50 value greater than 5000 mg/kg BW, suggesting it as a non-toxic substance. Furthermore, repeated administration of Galatonol for 90 days did not lead to any abnormalities or signs of toxicity in the animals tested.


4. Proven Benefits through Pre-clinical Study

The benefits of Galatonol in increasing breast milk production have been studied through pharmacodynamic study. 

Key Feature of the Product

Galatonol

In a preclinical study involving female lactating rats, the administration of Galatonol resulted in a significant increase in breast milk production compared to the untreated control group (p < 0.05). This increase also positively impacted the body weight of the pups. Additionally, the levels of prolactin and oxytocin were significantly higher in the treated groups compared to the control group (p < 0.05). Accordingly, the increase in breast milk production was associated with the increase in prolactin and oxytocin secretion.


Coleus amboinicus herba

Coleus amboinicus, also known as bangun-bangun herb, is traditionally used to increase breast milk production by making soup or brewing it with boiling water. This benefit has also been documented in the Decree of the Minister of Health of the Republic of Indonesia Number HK.01.07/Menkes/187/2017 regarding the Formularium Ramuan Obat Tradisional Indonesia.


Sauropus androgynus folium

Sauropus androgynus, commonly known as daun katuk, is traditionally consumed by Indonesians and is believed to increase breast milk production during lactation. Lactation, a process of milk synthesis and secretion, occurs with the help of 2 hormones, prolactin and oxytocin. Several studies have proven the benefits of S. androgynus leaves for increasing breast milk production. Supplementation of mature S. androgynus leaf extracts (173.6 mg /kg) on lactating BALB/C mice increased the expression of prolactin and oxytocin gene by 15.75 and 25.77 fold, respectively, compared to the control group. The results suggested that mature S. androgynus leaf extract significantly increased the expressions of both genes in lactating BALB/C mice (Soka et al., 2010). Similar research results also show that S. androgynus leaves extract (6 mg/kg) increases the mother's breast milk production up to 50.7% compared with placebo in lactating woman subjects (Sa’roni et al., 2004). 

Health Benefit

Store at room temperature (≤ 30°C), in a tight container, protect from direct sunlight.

Storage Conditions

  1. Minister of Health of the Republic of Indonesia. 2017. Formularium Ramuan Obat Tradisional Indonesia. 

  2. Suryawan, A. Z. and Lazarosony, N. R. 2021. The effect of Katuk Leaf to breastfeeding mother: a literature review. Indonesian Society Of Perinatology 2(2): 25-28

  3. Soka, S., Alam, H., Boenjamin, N., Agustina T. W., Sugartono, M. T. 2010. Effect of Sauropus androgynus leaf extracts on the expression of prolactin and oxytocin genes in lactating BALB/C mice. Journal of Nutrigenetics and Nutrigenomics. Vol 3(1): 31 - 36. https://doi.org/10.1159/000319710.

  4. Sa’roni, Sadjimin, T., Sja’bani, M., Zulaela. 2004. Effectiveness of the Sauropus androgynus (L.) Merr Leaf Extract in Increasing Mother’s Breast Milk Production.

Reference

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