

Andrographis paniculata extract
Andrographis paniculata extract is our generic extract that contains Andrographis paniculata herb, referred to as herba sambiloto. In traditional Indonesian medicine, Andrographis paniculata is widely used for its various health benefits, including the treatment of fever, infections, inflammation, and digestive disorders.
Product Overview
Botanical origin
Andrographis paniculata herb
Type of extract
Dry extract
Analytical marker: Andrographolide
Customized Drug Extract Ratio (DER) from 20:1 (genuine extract) up to 5:1.
Product Specification
1. Premium Quality and Standardization
Andrographis paniculata herb is a standardized herbal generic extract crafted to meet stringent quality specifications.
2. Manufactured in a Certified Facility
Produced in a facility with GMP, CPOTB, IEBA and ISO 22000 certifications, ensuring top-tier quality.
Guaranteed Halal through the implementation of the Halal Assurance System.
3. Non-toxic Extract
Based on literature studies, the acute toxicity of Andrographis paniculata extract administered alone in rats was investigated by Chandrasekaran et al. in 2009. The study found that administering Andrographis paniculata extract at doses up to 5000 mg/kg of body weight did not result in any signs of toxicity in the test animals. Therefore, Andrographis paniculata extract can be classified as safe. In another acute toxicity study involving rats, the ethanolic extract of A. paniculata herbs combined with G. procumbens leaves was categorized as unclassified (>2000 mg/kg body weight) in terms of toxicity levels according to the Globally Harmonized Classification System. The results indicated that exposure to this combination did not cause any toxic symptoms, and no animals died as a result. A histological examination of the liver showed no significant damage, even after exposure to a dose of 2000 mg/kg body weight. Additionally, there were no notable changes in clinical observations related to the skin and fur, mucous membranes, respiratory system, circulatory system, somatomotor system, eyes, autonomic system, or behavior. All test animals remained normal, and no abnormalities in behavior were observed in any treatment groups.
Key Feature of the Product
Andrographis paniculata, commonly known as sambiloto, has been traditionally used in various herbal remedies, particularly in Southeast Asia. Empirically, it is believed to treat fever, infections, liver disorders, and digestive issues. It is also widely used to boost immunity, reduce inflammation, help lower blood sugar, and improve respiratory health. Additionally, it has been used in traditional medicine for its antimicrobial and antiviral properties, particularly in treating hepatitis, malaria, and sore throats.
Health Benefit
Store at room temperature (≤ 30°C), in a tight container, protect from direct sunlight.
Storage Conditions
Sari K. R. P., et al. 2020. Studi toksisitas akut kombinasi ekstrak daun Andrographis paniculata (Burm.f) dan Gynura procumbens (Merr). Jurnal Ilmiah Farmasi 16(1), 1-89. Link: https://journal.uii.ac.id/JIF/article/view/14077/10192
Acuan Sediaan Herbal Volume III dan IV
Cabe Puyang Warisan Nenek Moyang Vol.2
Simplifikasi BPOM
Formularium Obat Herbal Asli Indonesia
WHO Vol.2
